Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Carnitine: Top 3 Anti Aging Benefits of This Super Nutrient Metabolism: Master the Carnitine Shuttle and Stop Exam Stress! Long Chain Fatty Acids (LCFAs) love to burn energy, but they face a major obstacle: they cannot enter the mitochondrial matrix where Beta Oxidation Carnitine Deficiency: What Is It, Causes, Symptoms, and More Osmosis The mechanism by which long chain fatty acids enter the mitochondria. Download Scientific Diagram